
317318-70-0
- Product Name:GW-501516?/?Cardarine
- Molecular Formula:C21H18F3NO3S2
- Purity:99%
- Molecular Weight:453.50
Product Details;
CasNo: 317318-70-0
Molecular Formula: C21H18F3NO3S2
Appearance: white solid
Manufacturer supply high quality GW-501516?/?Cardarine 317318-70-0 with ISO standards We provide high quality 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid (CAS 317318-70-0), at a very affordable prices to our customers.
1.What is the 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid ?
Peroxisome proliferator-activated receptor δ (PPARδ) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. GW 501516 is the first highly selective synthetic PPARδ agonist available. GW 501516 binds to human PPARδ with an IC50 value of 1 nM, and is at least 100-fold selective for PPARδ compared to PPARα and PPARγ. In obese primates, GW 501516 increases high density lipoprotein cholesterol and apolipoprotein A-1 specific reverse cholesterol transport. GW 501516 is therefore a model compound for a new type of obesity therapeutic, as well as a selective pharmacological tool for understanding lipid metabolism.
GW501516 has been used to study its effect on mutation-driven colorectal tumorigenesis and tumor invasion using mouse model.
2.What is the CAS number for 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid ?
The CAS number of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid is 317318-70-0.
More information of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid 317318-70-0 are:
CAS Number |
317318-70-0 |
Density |
1.426 g/cm3 |
Melting Point |
134-136°C |
Boiling Point |
584.543 °C at 760 mmHg |
Flash Point |
307.321 °C |
Vapor Pressure |
0mmHg at 25°C |
Refractive Index |
1.619 |
PSA |
112.96000 |
LogP |
6.20140 |
Pka |
3.17±0.10(Predicted) |
3.What is the molecular formula of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid ?
The chemical formula of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid is C21H18F3NO3S2 which containing 21 Carbon atoms,18 Hydrogen atoms,3 Fluorine atoms,1 Nitrogen atoms,3 Oxygen atoms and 2 Sulfur atoms,and the molecular weight, and the molecular weight of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid is 453.50
4.What is 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid(317318-70-0)used for?
Peroxisome proliferator-activated receptor δ (PPARδ) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. GW 501516 is the first highly selective synthetic PPARδ agonist available. GW 501516 binds to human PPARδ with an IC50 value of 1 nM, and is at least 100-fold selective for PPARδ compared to PPARα and PPARγ. In obese primates, GW 501516 increases high density lipoprotein cholesterol and apolipoprotein A-1 specific reverse cholesterol transport. GW 501516 is therefore a model compound for a new type of obesity therapeutic, as well as a selective pharmacological tool for understanding lipid metabolism.
InChI:InChI=1/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)
Relevant articles related to 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid:
5.Manufacturer supply high quality GW-501516?/?Cardarine 317318-70-0 with ISO standards
Maisheng Hebei Technology Co., Ltd. is a quality supplier of 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid 317318-70-0.
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